The Effect on Blood Glucose in Mice of Xiao Tang 2 and Xiao Tang 5

Objective:To observe the effect of Xiao Tang 2 and Xiao Tang 5 on blood glucose in mice. Methods: The model of hyperglucemia mice was established by injecting Alloxan intraabdominal cavityly; Effect of Xiao Tang 2 and Xiao Tang 5 blood glucose in diabetes and normal mice and on glucose tolerance of mice was observed. Results: At the end of the experiment, the introgastric administration of Xiao Tang 5 at the dosage of 1.6?g crude drug/kg can be highly effective in lowering blood glucose in hyperglucemia mice and decrease the blood glucose in normal mice. Compared with Xiao Tang 5, Xiao Tang 2 was not significant effect on blood glucose in diabetes and normal mice and on glucose tolerance of mice. Conclusion: Only Xiao Tang 5 can significantly reduce blood glucose in mice.