2014•China Modern MedicineRequires access
Influence of danhong injection on serum IL-8,IL-18 and TNF-α concentration in patient with cerebral infarction
XU Bing-cha
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Abstract
Objective To explore influence of danhong injection on serum IL-8,IL-18 and TNF-α concentration in patient with cerebral infarction.Methods 60 patients were divided into control group and observation group,each group of 30 cases.Ordinary therapy was used in control group,ordinary therapy and danhong injection were used in observation group.Serum IL-8,IL-18 and TNF-α concentration of patient with cerebral infarction were measured at days 1,2,3,5 and 7 after admission by RIA or ELISA.The effect of two groups was compared.Results Total effective rate of observation group was 96.7%,total effective rate of control group was 53.3%,with statistical difference(P0.05).At the time of admission,serum IL-8,IL-18 and TNF-α concentration of two groups was compared respectively,with no statistical difference(P0.05).At days 1,2,3,5 and 7 after admission,serum IL-8,IL-18 and TNF-α concentration of observation group was significantly lower than that of control group respectively,with statistical difference(P0.05).Conclusion Danhong injection can inhibit inflammatory reaction in ischemic brain tissue of patient with cerebral infarction,so as to improve neurological function.