The relationship between serum high-sensitivity C-reactive protein level and severity of coronary heart disease

Objective To explore the relationship and significance between serum high-sensitivity C-reactive protein(hs-CRP) level and coronary heart disease(CHD). Methods 84 patients diagnosed with CHD by coronary angiography ,32 patients with stable angina,40 patients with unstable angina,12 patients with acute myocardial infarction,50 healthy persons as normal control group.Their serum hs-CRP levels were determined by scatter velocity turbidimethy.Results The hs-CRP level were increased progressively.in normal control group, stable angina group unstable angina group and acute myocardial infarction group the hs-CRP level in the stable angina group were significantly higher than that of the normal control group(P0.01). the hs-CRP levels in the unstable angina group and the acute myocardial infarction group were significantly higher than that of normal control group and stable angina group(P0.01).Conclusions The patients with coronary heart disease have higher levels of serum hs-CRP and it is another independend risk factor of coronary heart disease.The coronary heart disease is related to inflammation of atherosclerosis plaque in coronary artery.hs-CRP may be the predictor factor of patients condition in coronary heart disease.