2012•Chinese Journal of Hospital PharmacyRequires access

Comparison of effects of dinoprostone vaginal suppositories and misoprostol tablets and oxytocin on induced labor in postterm pregnant patients

Cheng Ying

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Abstract

OBJECTIVE To compare the effects of dinoprostone vaginal suppositories and misoprostol tablets and oxytocin on cervical ripening and induced labor in postterm pregnant patients.METHODS 273 postterm pregnant women who required induction of labor in our hospital were randomly divided into observation group and control group 1 and controt group 2.The cervical ripening and delivery outcome were observed.RESULTS The observation group 12 h cervical ripening efficiency was 90.11%,higher than the control group 1 and control group 2(278.02%,80.22%),the difference was significant(χ2=4.16,P0.05).The observation group regardless of medication to time in labor,or labor were lower than those of control group 1 and control group 2,the difference was significant(χ2=3.84,P0.05;χ2=4.30,P0.05);the success rate was significantly better than the control group 1 and control group 2,the difference has statistical significance(χ2=9.53,P0.01).The mode of delivery,between the three groups had no significant difference,(χ2=1.02,P0.05).CONCLUSION Dinoprostone vaginal suppositories is superior to oxytocin oncervical ripening and labor induction in postterm pregnancy.It's safe and convenient.

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OBJECTIVE To compare the effects of dinoprostone vaginal suppositories and misoprostol tablets and oxytocin on cervical ripening and induced labor in postterm pregnant patients.METHODS 273 postterm pregnant women who required induction of labor in our hospital were randomly divided into observation group and control group 1 and controt group 2.The cervical ripening and delivery outcome were observed.RESULTS The observation group 12 h cervical ripening efficiency was 90.11%,higher than the control group 1 and control group 2(278.02%,80.22%),the difference was significant(χ2=4.16,P0.05).The observation group regardless of medication to time in labor,or labor were lower than those of control group 1 and control group 2,the difference was significant(χ2=3.84,P0.05;χ2=4.30,P0.05);the success rate was significantly better than the control group 1 and control group 2,the difference has statistical significance(χ2=9.53,P0.01).The mode of delivery,between the three groups had no significant difference,(χ2=1.02,P0.05).CONCLUSION Dinoprostone vaginal suppositories is superior to oxytocin oncervical ripening and labor induction in postterm pregnancy.It's safe and convenient.

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Available abstract

OBJECTIVE To compare the effects of dinoprostone vaginal suppositories and misoprostol tablets and oxytocin on cervical ripening and induced labor in postterm pregnant patients.METHODS 273 postterm pregnant women who required induction of labor in our hospital were randomly divided into observation group and control group 1 and controt group 2.The cervical ripening and delivery outcome were observed.RESULTS The observation group 12 h cervical ripening efficiency was 90.11%,higher than the control group 1 and control group 2(278.02%,80.22%),the difference was significant(χ2=4.16,P0.05).The observation group regardless of medication to time in labor,or labor were lower than those of control group 1 and control group 2,the difference was significant(χ2=3.84,P0.05;χ2=4.30,P0.05);the success rate was significantly better than the control group 1 and control group 2,the difference has statistical significance(χ2=9.53,P0.01).The mode of delivery,between the three groups had no significant difference,(χ2=1.02,P0.05).CONCLUSION Dinoprostone vaginal suppositories is superior to oxytocin oncervical ripening and labor induction in postterm pregnancy.It's safe and convenient.

Key concepts: Dinoprostone, Misoprostol, Oxytocin, Medicine, Obstetrics, Ripening, Labor induction, Vaginal delivery

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Comparison of effects of dinoprostone vaginal suppositories and misoprostol tablets and oxytocin on induced labor in postterm pregnant patients — Research Paper | ScholarLens