Comparison of Effects of Dinoprostone Vaginal Suppositories and Oxytocin on Induced Labor in Term Pregnancy

Objective To compare the effects of dinoprostone vaginal suppositories and oxytocin on cervical ripening and induced labor in term pregnancy.Methods One hundred and sixty term pregnant women who required induction of labor from Jan.2008 to Jun.2011 in our hospital were randomly divided into observation group(80 cases) and control group(80 cases);The dinoprostone suppositories was put into the posterior fornix of pregnant women in observation group,and small dose oxytocin was dripped in vein of pregnant women in control group;the Bishop scores,success rate of induced labor,modes of delivery and influence of mater and neonate were compared between the two groups.Results The efficacy of cervical ripening,the rate of successful labor induction,the average time from medication to in labor and the rate of cesarean section in observation group were 93.75%,88.75%,(10.99±3.44)h and 15%.The efficacy of cervical ripening,the rate of successful labor induction,the average time from medication to in labor and the rate of cesarean section in control group were 62.5%,53.75%,(38.84±13.95)h and 51.25%.It was significantly different between the two groups(P0.001).While,there was no significant difference in outcome of mater and neonate between the two groups.Conclusion Dinoprostone vaginal suppositories is superior to oxytocin on cervical ripening and labor induction in term pregnancy.It's safe and convenient.It deserves to promote the application in clinic.