Comparative study and deviation evaluation the results of ALT detected by two biochemical detection systems

Objective To develop the contrast test and deviation evaluation to ALT results which detected by 2 biochemical detection systems,and explored the comparability of the 2 methods.Method According to EP9-A document of NCCLS,Roche INTEGRA 400 Plus detection system as control,OLIMPUS AU640 detection system was the empirical method,alanine aminotransferase(ALT) in 40 fresh sera were measured by the 2 methods,calculated the correlation coefficient,linear regression equation and expectant deviation,the results which detected by the 2 methods were evaluated according to CLIA'88,judgment the clinical acceptability of the 2 methods.Results The correlation coefficient R1 was 0.9990.975,R2 was 0.9990.95,correlation was well,the expectant deviation in 1/2 of CLIA88 allowable error.Conclusions The ALT results detected by Roche INTEGRA 400 Plus and OLIMPUS AU640 had comparability,and it can be detected by the 2 detection systems.