Comparable research on alanine aminotransferase results among different kinds of detection system

Objective To study the comparability of alanine aminotransferase (ALT) results among different detection systems. Methods Three different kinds of biochemistry detection system, with enzyme method, were used to detect ALT concentrations in 2 kinds of Randox quality controls (level 2 and level 3) and 45 serum specimens. The collected data were dealt with statistical analysis. Results Analysis of variance showed the ALT results from different control and patients sera had significant difference in different detection systems (P0.001). The correlation coefficient of each detection system was above 0.975 and the reliability coefficient of them were close to 1. We regarded detection system 1 as target detection system and evaluated the acceptability of other detection systems. As a result, detection system 2 was accepted and detection system 3 was partly accepted by clinic assessment. Conclusions The precision of ALT results in the 3 kinds of detection systems accords with clinical requirement. Comparability exists in the evaluation of clinical acceptability except detection system 3.