Efficacy of Creatine Phosphate Sodium Combined with Fructose Diphosphate Sodium on Viral Myocarditis

Objective To explore the clinical outcome of creatine phosphate sodium combined with fructose diphosphate sodium for treatment of viral myocarditis. Methods In this case series,from September 2010to August 2012,99 cases of viral myocarditis from North Hospital of People's Hospital of Xinjiang Uygur Autonomous Region,were selected and randomly divided into combination group( 50 cases) and treatment group( 49cases),both of the two groups of patients were given the conventional therapy,the treatment group received sodium creatine phosphate 150 mg / kg,2 times a day,intravenously; and the combination group received fructose sodium diphosphate 50 mg / kg,intravenouslyfor two weeks. Results After treatment,the total efficiency of the combination group was 92. 0 %,higher than the treatment group( 67. 3%) with significant differences( Z =2. 484,P 0. 05). After treatment,ECG and myocardial enzymes did not change after treatment in one case each in the combination group; 4 cases of ECG and 7 cases of myocardial enzymes in the treatment group did not change after treatment. Improvement of the combination group was significantly better than the treatment group. Conclusion Application of the creatine phosphate sodium combined with fructose diphosphate sodium is an effective method to treat viral myocarditis,which is safe and feasible,with mild adverse reactions,thus is worthy of clinical promotion.