ScholarLens Back to search
2011•Chinese Journal of Birth Health & HeredityRequires access

Retrospective analysis of prenatal screening on 9338 cases in the city of Quanzhou

FU Qing-li

Open publisher page 0 citations

Abstract

Objective: To evaluate the clinic value of the double marker prenatal screening system for Down′s syndrome(DS),trisomy 18 and neural tube defects(NTD).Methods: Double label time-resolved fluorescence method was used to test the concentrations of AFP and Free-β-hCG in the serum of 9338 middle period pregnant women who were pregnant for 15-20+6 weeks.combined with gestational age,weight,age and other factors,we evaluated the risk assessment with assessment software.Results: In 9338 cases,the positive rate 4.7%(437/9338),with 2.8%(262 cases)of Downs syndrome and 1.3%(119 cases) of NTD and 0.6%(56 cases) of 18-trisome syndrome.Conclusion: The combination of the serum biochemistry results of AFP and Free-β-hCG can effectively reduce congenital fetal malformtion.

About this research paper

What this paper is about

Objective: To evaluate the clinic value of the double marker prenatal screening system for Down′s syndrome(DS),trisomy 18 and neural tube defects(NTD).Methods: Double label time-resolved fluorescence method was used to test the concentrations of AFP and Free-β-hCG in the serum of 9338 middle period pregnant women who were pregnant for 15-20+6 weeks.combined with gestational age,weight,age and other factors,we evaluated the risk assessment with assessment software.Results: In 9338 cases,the positive rate 4.7%(437/9338),with 2.8%(262 cases)of Downs syndrome and 1.3%(119 cases) of NTD and 0.6%(56 cases) of 18-trisome syndrome.Conclusion: The combination of the serum biochemistry results of AFP and Free-β-hCG can effectively reduce congenital fetal malformtion.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To evaluate the clinic value of the double marker prenatal screening system for Down′s syndrome(DS),trisomy 18 and neural tube defects(NTD).Methods: Double label time-resolved fluorescence method was used to test the concentrations of AFP and Free-β-hCG in the serum of 9338 middle period pregnant women who were pregnant for 15-20+6 weeks.combined with gestational age,weight,age and other factors,we evaluated the risk assessment with assessment software.Results: In 9338 cases,the positive rate 4.7%(437/9338),with 2.8%(262 cases)of Downs syndrome and 1.3%(119 cases) of NTD and 0.6%(56 cases) of 18-trisome syndrome.Conclusion: The combination of the serum biochemistry results of AFP and Free-β-hCG can effectively reduce congenital fetal malformtion.

Key concepts: Prenatal screening, Trisomy, Medicine, Down syndrome, Fetus, Prenatal diagnosis, Obstetrics, Gestational age

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Retrospective analysis of prenatal screening on 9338 cases in the city of Quanzhou — Research Paper | ScholarLens