CT Perfusion Imaging in the Diagnosis of Glioma

Objective: To investigate the value of CT perfusion imaging in the diagnosis of glioma.Method: Selected 50 cases of glioma patients inspected in the hospital imaging center from March 2010 to July 2011,All patients underwent CT perfusion scanning,reconstruction of CT perfusion images to measure the ROI of cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT),and measure the microvessel density in pathologic specimens.Result: The mean value of CBF,CBV and PS were significantly higher in high-grade gliomas group than the group of low-grade gliomas,and the differences were statistically significant(P 0.01).Group of high-grade gliomas and low-grade gliomas group MTT had no significant difference between the mean value(P 0.05).Through spearman correlation analysis,the glioma CT perfusion rCBV values with MVD has a significant positive correlation(r=0.571,P0.05).Conclusion: The high-grade gliomas and low-grade gliomas CT perfusion imaging parameters has significant differences,There's a significant positive correlation between rCBV and MVD.