Clinical analysis of rivanol combined with mifepristone and misoprostol for induced abortion

Objective: To explore the clinical effects of rivanol combined with mifepristone and misoprostol for termination of pregnancy. Methods: 209pregnant women required termination between 2008 and 2012 in our hospital were divided into observational group( n = 109) and control group( n = 100)according to sequence on admission. Patients in observational group received rivanol combined with mifepristone and misoprostol,and those in control group were given combined use of rivanol with mifepristone. Two groups were assessed and compared regarding the outcomes of induced labor,placental expulsion time,labor pain in induction,postpartum hemorrhage and incidence of laceration of cervix and other adverse effects。Results: The two groups went through complete termination of pregnancy. The time of placental expulsion and birth process were shorter,and postpartum bleeding volume,incidence of abdominal pain were significantly lower in the observational group as compare with the control group( P 0. 05),whereas the incidence of adverse effects showed no significant difference for the two groups. Conclusion: Rivanol combined with either mifepristone or misoprostol or both the latter agent can be safely used for induced abortion in mid-pregnancy with reduced labor pain and less postpartum bleeding besides shortened birth process.