Application of Multi-Tumor Markers Protein Biochip Diagnostic System in Tumor

Objective:To study the value of protein chip system for multi-tumor markers detection in the diagnosis of tumor.Methods:We screened for 12 tumor biomarkers in samples from a known cancer group of 43 cancer patients at different clinical stages,and from control group of 46 healthy people,and 29 patients with benign disease.Results:51 results,which was 80.95 percent of 63 cancer patients,were detected abnormally by protein biochip,the tumor group had significantly higher positive rate than that of the controls.Nine abnormal results beyond reference ranges were found in 46 healthy controls,the positive rate was 19.57%.Conclusions:The higher sensitivity and specificity achieved by the combined use of the selected biomarkers especially show great potential for the early detection of the cancers.Application of multi-tumor markers protein biochip is helpful for the earlier diagnosis in tumor.