Screening Earlier Tumor and Monitoring Therapies by Protein Biochip Technology of Multi-tumor Markers

Objective To evaluate the multi-tumor markers system on screening earlier tumor and monitoring therapies by protein biochip technology.~Methods Using the multi-tumor markers protein biochip diagnostic system to determine and analyze the concentration values of 12 tumor markers (AFP, CEA, NSE, CA125, CA153, CA242, CA199, PSA, f-PSA, FER, β-HCG and HGH) from control group of 282 healthy people, 185 cases of clinical detected cancer patients at different clinical stages, and 136 detected cancer patients under post-operation monitoring.~Results 2 abnormal results beyond reference ranges were found in 282 healthy controls, which were finally diagnosed earlier period tumor by follow-up survey(positive ratio was 0.71%),153 out of 185 cancer patients at different clinical stages were abnormal (positive ratio was 82.70%),in addition, there were 11 abnormal results l in 136 detected cancer patients under post-operation monitoring.Conclusion The multi-tumor markers protein biochip diagnostic system may take a significant role in screeing tumor and observing recurrence and metastasis.