2007Journal of Jingmen Technical CollegeRequires access

Determination of Furacillini Content in Furaclin and Ephedrine Nasaldrops by UV Spectrophotometry

Tan Xi-jun

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Abstract

Objective:To develop a method for determination of Furacillini content in Furaclin and Ephedrine nasal drops.Methods:UV spectophotometry of Furacillini at 374 nm was caculated for the assay.Results:There was a good linear relation between Furacillini content in the range of 4.8 to 7.2 μg.ml-1(r=0.999 9).The average recovery was 100.3% with RSD of 0.53%.Conclusion:The develop method is simple and accurate without interference from Dyclonine and Ointment,which could be used in the quality control of this product.

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Objective:To develop a method for determination of Furacillini content in Furaclin and Ephedrine nasal drops.Methods:UV spectophotometry of Furacillini at 374 nm was caculated for the assay.Results:There was a good linear relation between Furacillini content in the range of 4.8 to 7.2 μg.ml-1(r=0.999 9).The average recovery was 100.3% with RSD of 0.53%.Conclusion:The develop method is simple and accurate without interference from Dyclonine and Ointment,which could be used in the quality control of this product.

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Available abstract

Objective:To develop a method for determination of Furacillini content in Furaclin and Ephedrine nasal drops.Methods:UV spectophotometry of Furacillini at 374 nm was caculated for the assay.Results:There was a good linear relation between Furacillini content in the range of 4.8 to 7.2 μg.ml-1(r=0.999 9).The average recovery was 100.3% with RSD of 0.53%.Conclusion:The develop method is simple and accurate without interference from Dyclonine and Ointment,which could be used in the quality control of this product.

Key concepts: Ephedrine, Chromatography, Chemistry, Content determination, Spectrophotometry, Content (measure theory), Analytical Chemistry (journal), High-performance liquid chromatography

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