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2007•Journal of Taishan Medical CollegeRequires access

Study of function and mechanism on K562/ADM cells by Haishengsu

Shuangfeng Chen

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Abstract

Objective: To study the inhibitory action and the effect on apoptosis associated protein on K562/ADM cells by Haishengsu.Methods: The procedure of MTT assay was used to determine the inhibitory action on k562/ADM cells,and immunocytochemistry was used to detect the expression of bcl-2 and bax protein.Results: Haishengsu could inhibit the proliferation of K562/ADM cells,and could down-regulate the expression of bcl-2 protein and up-regulate the expression of bax protein on k562/ADM cells.Conclusion: Haishengsu can obviously inhibit the proliferation of K562/ADM cells and affect the expressions of bcl-2 and bax protein.

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What this paper is about

Objective: To study the inhibitory action and the effect on apoptosis associated protein on K562/ADM cells by Haishengsu.Methods: The procedure of MTT assay was used to determine the inhibitory action on k562/ADM cells,and immunocytochemistry was used to detect the expression of bcl-2 and bax protein.Results: Haishengsu could inhibit the proliferation of K562/ADM cells,and could down-regulate the expression of bcl-2 protein and up-regulate the expression of bax protein on k562/ADM cells.Conclusion: Haishengsu can obviously inhibit the proliferation of K562/ADM cells and affect the expressions of bcl-2 and bax protein.

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Available abstract

Objective: To study the inhibitory action and the effect on apoptosis associated protein on K562/ADM cells by Haishengsu.Methods: The procedure of MTT assay was used to determine the inhibitory action on k562/ADM cells,and immunocytochemistry was used to detect the expression of bcl-2 and bax protein.Results: Haishengsu could inhibit the proliferation of K562/ADM cells,and could down-regulate the expression of bcl-2 protein and up-regulate the expression of bax protein on k562/ADM cells.Conclusion: Haishengsu can obviously inhibit the proliferation of K562/ADM cells and affect the expressions of bcl-2 and bax protein.

Key concepts: K562 cells, Immunocytochemistry, Apoptosis, Inhibitory postsynaptic potential, BAX Protein, Protein expression, Function (biology), Cell biology

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