Clinical efficacy analysis of thymosin treatment for 84 children with hand-foot-and-mouth disease

Objective To investigate the clinical efficacy of thymosin α1 treatment for children with hand-foot-and-mouth disease.Methods 84 hand-foot-and-mouth disease patients were randomly divided into two groups:control group(n=42)and treatment group(n=42).Control group was given conventional basic treatment and ribavirin,on the basis of the control group therapy,treatment group was treated with thymosin α1.The clinical effects,average hospitalization days,remission time of symptoms and signs,and the results blood index test in the two groups was observed and compared.Results The total effective rate in treatment group was significantly higher than that in control group(P0.05);the average hospitalization days,time of fever subsiding,foot and skin rash disappearing,oral herpes disappearing,salivation disappearing,and the appetite returning in the treatment group after treatment were significantly shorter than those in control group(P0.05);the index value of hs-CRP,IgM in treatment group reduced more significantly than that in control group(P0.05);the index value of IgA,IgG in treatment group after treatment was significantly higher than that in control group(P0.05).Conclusion There is significant clinical efficacy of thymosin α1 in treatment for children with hand-foot-and-mouth disease.