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The Clinical Significance of Serum CEA and CA19-9 Levels for Gastric Cancer Staging

Qian Lei-mi

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Abstract

Objective To study the value of detection of serum CEA and CA19-9 in diagnosis and prognosis in patients with gastric cancer.Methods Serum levels of CEA and CA19-9 of gastric cancer patients at different stages were measured by electrochemiluminescence assay.Results The levels of two kinds of tumor marker in gastric cancer group at stage Ⅳ were obviously higher than those in three other groups(P0.01).The positive rate of serum CEA and CA19-9 was 31.1% and 39.5% respectively.The total positive rate of gastric cancer was 53.5%(CEA and/or CA19-9).Conclusion Positive correlation between serum levels of CEA or CA19-9 and the clinicopathological staging of gastric cancer was observed.The combined detection of CEA and CA19-9 can significantly improve the sensitivity of diagnosis of gastric cancer,which also has a certain value in monitoring patient′s condition and prognosis.

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What this paper is about

Objective To study the value of detection of serum CEA and CA19-9 in diagnosis and prognosis in patients with gastric cancer.Methods Serum levels of CEA and CA19-9 of gastric cancer patients at different stages were measured by electrochemiluminescence assay.Results The levels of two kinds of tumor marker in gastric cancer group at stage Ⅳ were obviously higher than those in three other groups(P0.01).The positive rate of serum CEA and CA19-9 was 31.1% and 39.5% respectively.The total positive rate of gastric cancer was 53.5%(CEA and/or CA19-9).Conclusion Positive correlation between serum levels of CEA or CA19-9 and the clinicopathological staging of gastric cancer was observed.The combined detection of CEA and CA19-9 can significantly improve the sensitivity of diagnosis of gastric cancer,which also has a certain value in monitoring patient′s condition and prognosis.

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Available abstract

Objective To study the value of detection of serum CEA and CA19-9 in diagnosis and prognosis in patients with gastric cancer.Methods Serum levels of CEA and CA19-9 of gastric cancer patients at different stages were measured by electrochemiluminescence assay.Results The levels of two kinds of tumor marker in gastric cancer group at stage Ⅳ were obviously higher than those in three other groups(P0.01).The positive rate of serum CEA and CA19-9 was 31.1% and 39.5% respectively.The total positive rate of gastric cancer was 53.5%(CEA and/or CA19-9).Conclusion Positive correlation between serum levels of CEA or CA19-9 and the clinicopathological staging of gastric cancer was observed.The combined detection of CEA and CA19-9 can significantly improve the sensitivity of diagnosis of gastric cancer,which also has a certain value in monitoring patient′s condition and prognosis.

Key concepts: Medicine, CA19-9, Internal medicine, Cancer, Tumor marker, Gastroenterology, Clinical significance, Carcinoembryonic antigen

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The Clinical Significance of Serum CEA and CA19-9 Levels for Gastric Cancer Staging — Research Paper | ScholarLens