2007•The Journal of Medical Theory and PracticeRequires access

Effects of Curcumin on Proliferation of Nasopharyngeal Carcinoma Cell Line(CNE-2Z-H5)

YU Jian-hu

Abstract

Objective:To investigate the effects of curcumin on growth and proliferation in CNE-2Z-H5 cells.Methods:Cells growth curves,MTT assay and plate colony formation rate were used to identify the effects of curcumin on growth and proliferation of CNE-2Z-H5 cells.Results:The growth and proliferation of CNE-2Z-H5 cells were inhibited significantly by curcumin compared with the control group,which was in dose dependent manner.At the same time when the dose of curcumin was higher,curcumin also could kill CNE-2Z-H5 cells obviously in vitro.Conclusion:The curcumin can inhibit the growth and proliferation of CNE-2Z-H5 cells effectively.It has applicable value in therapy of NPC.

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Key concepts: Curcumin, Nasopharyngeal carcinoma, Medicine, Cell growth, In vitro, Cancer research, Cell culture, Growth inhibition