2010•The Chinese Journal of Modern Applied PharmacyRequires access

Determination of Astragaloside IV in Aikefu Granules by HPLC-ELSD

Zhihong Zheng

Abstract

OBJECTIVE To establish a method for the determination of astragaloside Ⅳ in Aikefu granules by HPLC-ELSD.METHODS The content of astragaloside Ⅳ was determined by HPLC-ELSD.RESULTS A good linearity was observed for astragaloside Ⅳ in the range of 0.64-20.48 μg.The average recovery of astragaloside Ⅳ was 97.78% with RSD=1.12%(n=6).CONCLUSION The method is simple,accurate and reiable.It can be used for the quality control of granules.

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Key concepts: Astragaloside, High-performance liquid chromatography, Chromatography detector, Chromatography, Chemistry