2012Medical Journal of West ChinaRequires access

Distribution characteristics and resistance analysis of 352 strains of Acinetobacter baumannii

Jian Zhang

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Abstract

ObjectiveTo understand the distribution characteristics and drug resistance of Acinetobacter baumannii in clinical specimens.MethodsInfection and drug resistance of A.baumannii in our hospital from 2009 to 2010 was analyzed.352 strains of A.baumannii isolated from patients were identified by MicroScan Neg Combo Panel Type 31 and drug susceptibility tests were performed. Results283 strains(80.4%) of A.baumannii were examined from phlegm.163 strains(46.3%) of A.baumannii were from intensive care unit(ICU).56 strains(15.9%) from neurosurgery.A.baumannii had a higher susceptibility to sulbactam/cefoperazone(95%),and to other cephalosporins antibiotics the resistance rate was more than 60%.ConclusionA.baumannii infection is the main pathogenic bacteria in hospital,especially in the ICU.A.baumanii is forming multiple antibiotic resistance in the process of treatment.Sulbactam/cefoperazone is as first-line antimicrobial agents to treat patients with multiple resistance of A.baumannii infection.

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ObjectiveTo understand the distribution characteristics and drug resistance of Acinetobacter baumannii in clinical specimens.MethodsInfection and drug resistance of A.baumannii in our hospital from 2009 to 2010 was analyzed.352 strains of A.baumannii isolated from patients were identified by MicroScan Neg Combo Panel Type 31 and drug susceptibility tests were performed. Results283 strains(80.4%) of A.baumannii were examined from phlegm.163 strains(46.3%) of A.baumannii were from intensive care unit(ICU).56 strains(15.9%) from neurosurgery.A.baumannii had a higher susceptibility to sulbactam/cefoperazone(95%),and to other cephalosporins antibiotics the resistance rate was more than 60%.ConclusionA.baumannii infection is the main pathogenic bacteria in hospital,especially in the ICU.A.baumanii is forming multiple antibiotic resistance in the process of treatment.Sulbactam/cefoperazone is as first-line antimicrobial agents to treat patients with multiple resistance of A.baumannii infection.

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Available abstract

ObjectiveTo understand the distribution characteristics and drug resistance of Acinetobacter baumannii in clinical specimens.MethodsInfection and drug resistance of A.baumannii in our hospital from 2009 to 2010 was analyzed.352 strains of A.baumannii isolated from patients were identified by MicroScan Neg Combo Panel Type 31 and drug susceptibility tests were performed. Results283 strains(80.4%) of A.baumannii were examined from phlegm.163 strains(46.3%) of A.baumannii were from intensive care unit(ICU).56 strains(15.9%) from neurosurgery.A.baumannii had a higher susceptibility to sulbactam/cefoperazone(95%),and to other cephalosporins antibiotics the resistance rate was more than 60%.ConclusionA.baumannii infection is the main pathogenic bacteria in hospital,especially in the ICU.A.baumanii is forming multiple antibiotic resistance in the process of treatment.Sulbactam/cefoperazone is as first-line antimicrobial agents to treat patients with multiple resistance of A.baumannii infection.

Key concepts: Acinetobacter baumannii, Cefoperazone, Medicine, Sulbactam, Microbiology, Drug resistance, Antibiotics, Cephalosporin

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