Clinical distribution of 292 strains of acinetobacter baumannii and drug resistance

OBJECTIVE To understand the distribution characteristics and drug resistance of Acinetobacter baumannii in clinical specimens.METHODS Totally 292 strains of A.baumannii from patients from Jul 1st 2009 and Jun 30th,2010 were analyzed to calculate the ratio of sample source,patient unit origin and drug sensitivity as well as Pan-drug resistant A.baumannii.RESULTS A.baumannii isolated from ICU(Intensive Care Unit),neurosurgery department,respiratory department,and neurology department accounted for 74.3% of whole hospital and mostly originated from sputum(82.6%)of all A.baumannii samples.99.3% of them were susceptible to Polymyxin E,74.0% of them susceptible to Cefoperazone/sulbactam and 68.2% susceptible to Imipenem.But the resistance rate of other antibiotics was about 50%.The ratio of Pan-drug resistant A.baumannii was as high as 30.1%.CONCLUSION A.baumannii strains are the predominant opportunistic pathogenic bacteria in nosocomial infection,which are highly resistant and multidrug-resistant to antibiotics.Early antimicrobial agents susceptibility test is helpful to prevent and control A.baumannii nosocomial infection.