Distribution and drug resistance of 1120 strains of Acinetobacter baumannii

OBJECTIVE To investigate the distribution and drug resistance of Acinetobacter baumannii isolates and to provide basis for clinical application of antibiotics.METHODS The data on 1120 strains of A.baumannii from Jan 2009 to Jun 2011 were collected and reviewed to analyze the changes in distribution and drug resistance.RESULTS Of totally 1120 strains of A.baumannii isolated,253(8.9%) were isolated in 2009,444(10.1%) in 2010,and 423(14.6%) in 2011;the specimens were mainly obtained from the respiratory tract,accounting for 76.7%,A.baumannii isolates were primarily from the ICU,neurosurgery department and department of respiratory medicine,accounting for 36.9%,12.2%,and 9.3%,respectively;the antimicrobial susceptibility testing showed that the drug resistance rates of A.baumannii were relatively low to cefoperazone/sulbactam except 15 other antibiotics and increased year by year.CONCLUSION Both the detection rate and the drug resistance of A.baumannii increased year by year;the prevention and control of nosocomial infections should be strengthened,and the antibiotics should be used reasonably in order to decrease the drug resistant strains.