2002Shanxi Yike Daxue xuebaoRequires access

Detection and significance of platelet membrane glycoprotein CD62P and CD63 in patients with cerebral infarction

Kun Chen

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Abstract

Objective To investigate the clinical significance the platelet membrane glycoproteins in patients with cerebral infarction. Method The platelet membrane glycoprotein CD62P and CD63 of the peripheral blood from 68 patients with cerebral infarction and 20 healthy subjects were studied by flow cytometry. Results The positive rate of CD62P and CD63 in patients with cerebral infarction was higher than that in the normal. Moreover the positive rate of CD62P and CD63 in 3 days was higher than that in 14 days after stroke( P 0.01). Conclusion The platelet activation increases after cerebral stroke. Inhibition of platelet activation may be a way to prevent and treat cerebral infarction.

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Objective To investigate the clinical significance the platelet membrane glycoproteins in patients with cerebral infarction. Method The platelet membrane glycoprotein CD62P and CD63 of the peripheral blood from 68 patients with cerebral infarction and 20 healthy subjects were studied by flow cytometry. Results The positive rate of CD62P and CD63 in patients with cerebral infarction was higher than that in the normal. Moreover the positive rate of CD62P and CD63 in 3 days was higher than that in 14 days after stroke( P 0.01). Conclusion The platelet activation increases after cerebral stroke. Inhibition of platelet activation may be a way to prevent and treat cerebral infarction.

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Available abstract

Objective To investigate the clinical significance the platelet membrane glycoproteins in patients with cerebral infarction. Method The platelet membrane glycoprotein CD62P and CD63 of the peripheral blood from 68 patients with cerebral infarction and 20 healthy subjects were studied by flow cytometry. Results The positive rate of CD62P and CD63 in patients with cerebral infarction was higher than that in the normal. Moreover the positive rate of CD62P and CD63 in 3 days was higher than that in 14 days after stroke( P 0.01). Conclusion The platelet activation increases after cerebral stroke. Inhibition of platelet activation may be a way to prevent and treat cerebral infarction.

Key concepts: CD63, Cerebral infarction, Platelet, Platelet membrane glycoprotein, Medicine, Platelet activation, Internal medicine, Cardiology

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