Experimental studies of Huoluojiangu capsule on anti-inflammatory efficiency

Objective To observe the effect of Huoluojiangu Capsule(HJC) on anti-inflammatory experiment.Methods The anti-inflammatory experimental models were established in three kinds of rats with pleuritis,the swellen sole of the foot and the PGE_2 content in inflammatory tissues,respectively.Results The swollen reaction in the sole of foot in rats induced by egg white was lessoned with the treatment of low,middle and high dosage of HJC.Compared with the blank control group,the treatment is effective in low dosage group and evidently effective in groups of middle and high dosage after 30 min(P0.01).The effect of HJC is equivalent to that of diclofenac sodium.Compared with the blank control group,it was effective on the treatment of swollen reaction in the sole of foot in high dosage group(P0.001),effective in the middle dosage group(P0.05),and of no statistical significance in the low dosage group(P0.05),respectively.Compared with the blank control group,the effect of HJC on the PGE_2 content in the inflammatory tissues of middle and high dosage groups was significant(P0.001).The leucocyte effusion of pleural cavity in rats was inhibited in groups of middle and high dosage(P0.05).Conclusion The HJC shows good anti-inflammatory effect,and the effectiveness is basically equivalent to that of diclofenac sodium.