Changes of biliary bacteria and analysis of their sensitivity to antibiotics

Objective To investigate changes of biliary bacteria and their sensitivity to antibiotics in recent 10 years. Methods The data of 120 strains of aerobes found in 100 patients with positive bile culture from 1988 to 1998 and their sensitivity to antibiotics were statistically analyzed. Results The 120 strains of aerobes belonged to 34 species. Of these strains, 60% were mobile bacteria and 20.8% immobile ones. Among 21 cases of mixed infection, 7 were infected with pseudomonas aeruginosa. The bacteria were highly resistant to gentamycin and the 3rd generation of cephalosporins. However, they were highly sensitive to ciproloxacin and quinelone. The sensitivity of pseudomonas aeruginosa to these two agents was as high as 71.4%. Conclusions Now the bacterial species in the bile and their resistance to antibiotics are increased as compared with those in early 1980s.