2012•Liaoning Zhongyiyao Daxue xuebaoRequires access

A Preliminary Study on Protective Effects of Cyclovirohuxine D on Myocardial Ischemia-reperfusion Injury in Rats

Jia Wang

Abstract

Objective:To study the protective effects of Cyclovirohuxine D on myocardial ischemia-reperfusion injury in rats.Methods:30 SD rats were randomly divided into three groups:sham operative group,model group and Cyclovirohuxine D group.The activities of MDA and SOD were determined after myocardial ischemia 30min and reperfusion 60min.Results:Compared with model group,the level of MDA was decreased and level of SOD was increased in serum and cardiac muscle of Cyclovirohuxine D group.Conclusion:Protective effects of Cyclovirohuxine D on myocardial ischemia-reperfusion injury in rats is outstanding,which is possibly correlative with resisting lipid peroxides and clearing oxygen free radical.

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Key concepts: Medicine, Myocardial ischemia, Reperfusion injury, Ischemia, Internal medicine, Cardiac muscle, Anesthesia, Rat model