2013•Clinical Medicine & EngineeringRequires access

Clinical Study of Continuous Subcutaneous Insulin Infusion in the Treatment of Type 2 Diabetes

Wen Geng-qing

Open publisher page 0 citations

Abstract

Objective To study the efficacy and safety about continons subcutaneous insulin injection in the treatment of type 2 diabetes. Methods 100 cases of type 2 diabetic patients received oral hypoglycemic drug treatment and poor glucose control were randomly divided into the observation group and the control group. 50 patients in the observation group were treated with continuous subcutaneous insulin infusion therapy, the other 50 patients in the control group were treated with subcutaneous insulin injections therapy before meals. The efficacy and adverse reactions of two groups were compared and analyzed. Results In the observation group, the blood glucose time, insulin dosage and insulin dosage at blood sugar stable stage of were statistically lower than those in the control group (P0.05). The hypoglycemia reactive and dawn phenomenon of observation were lower than those of the control group, but with no significant difference between the two groups (P0.05). After treatment, the fasting blood glucose, postprandial 2 hour blood glucose and hemoglobin levels of the two groups significantly decreased (P0.05), but the observation group decreased even more significantly (P0.01), and those indicators were also significantly different between the two groups (P0.05). Conclusions Continuous subcutaneous insulin infusion is safe and effective in the treatment of type 2 diabetes, with low incidence of the deputy reaction such as hypoglycemia and dawn phenomenon.

About this research paper

What this paper is about

Objective To study the efficacy and safety about continons subcutaneous insulin injection in the treatment of type 2 diabetes. Methods 100 cases of type 2 diabetic patients received oral hypoglycemic drug treatment and poor glucose control were randomly divided into the observation group and the control group. 50 patients in the observation group were treated with continuous subcutaneous insulin infusion therapy, the other 50 patients in the control group were treated with subcutaneous insulin injections therapy before meals. The efficacy and adverse reactions of two groups were compared and analyzed. Results In the observation group, the blood glucose time, insulin dosage and insulin dosage at blood sugar stable stage of were statistically lower than those in the control group (P0.05). The hypoglycemia reactive and dawn phenomenon of observation were lower than those of the control group, but with no significant difference between the two groups (P0.05). After treatment, the fasting blood glucose, postprandial 2 hour blood glucose and hemoglobin levels of the two groups significantly decreased (P0.05), but the observation group decreased even more significantly (P0.01), and those indicators were also significantly different between the two groups (P0.05). Conclusions Continuous subcutaneous insulin infusion is safe and effective in the treatment of type 2 diabetes, with low incidence of the deputy reaction such as hypoglycemia and dawn phenomenon.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To study the efficacy and safety about continons subcutaneous insulin injection in the treatment of type 2 diabetes. Methods 100 cases of type 2 diabetic patients received oral hypoglycemic drug treatment and poor glucose control were randomly divided into the observation group and the control group. 50 patients in the observation group were treated with continuous subcutaneous insulin infusion therapy, the other 50 patients in the control group were treated with subcutaneous insulin injections therapy before meals. The efficacy and adverse reactions of two groups were compared and analyzed. Results In the observation group, the blood glucose time, insulin dosage and insulin dosage at blood sugar stable stage of were statistically lower than those in the control group (P0.05). The hypoglycemia reactive and dawn phenomenon of observation were lower than those of the control group, but with no significant difference between the two groups (P0.05). After treatment, the fasting blood glucose, postprandial 2 hour blood glucose and hemoglobin levels of the two groups significantly decreased (P0.05), but the observation group decreased even more significantly (P0.01), and those indicators were also significantly different between the two groups (P0.05). Conclusions Continuous subcutaneous insulin infusion is safe and effective in the treatment of type 2 diabetes, with low incidence of the deputy reaction such as hypoglycemia and dawn phenomenon.

Key concepts: Medicine, Hypoglycemia, Postprandial, Insulin, Hemoglobin, Blood sugar, Subcutaneous injection, Diabetes mellitus

Related papers

Back to paper searchBrowse research topicsOriginal source
Clinical Study of Continuous Subcutaneous Insulin Infusion in the Treatment of Type 2 Diabetes — Research Paper | ScholarLens