Clinical Study of Continuous Subcutaneous Insulin Infusion in the Treatment of Type 2 Diabetes
Wen Geng-qing
Abstract
Wen Geng-qing
Abstract
Objective To study the efficacy and safety about continons subcutaneous insulin injection in the treatment of type 2 diabetes. Methods 100 cases of type 2 diabetic patients received oral hypoglycemic drug treatment and poor glucose control were randomly divided into the observation group and the control group. 50 patients in the observation group were treated with continuous subcutaneous insulin infusion therapy, the other 50 patients in the control group were treated with subcutaneous insulin injections therapy before meals. The efficacy and adverse reactions of two groups were compared and analyzed. Results In the observation group, the blood glucose time, insulin dosage and insulin dosage at blood sugar stable stage of were statistically lower than those in the control group (P0.05). The hypoglycemia reactive and dawn phenomenon of observation were lower than those of the control group, but with no significant difference between the two groups (P0.05). After treatment, the fasting blood glucose, postprandial 2 hour blood glucose and hemoglobin levels of the two groups significantly decreased (P0.05), but the observation group decreased even more significantly (P0.01), and those indicators were also significantly different between the two groups (P0.05). Conclusions Continuous subcutaneous insulin infusion is safe and effective in the treatment of type 2 diabetes, with low incidence of the deputy reaction such as hypoglycemia and dawn phenomenon.
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Objective To study the efficacy and safety about continons subcutaneous insulin injection in the treatment of type 2 diabetes. Methods 100 cases of type 2 diabetic patients received oral hypoglycemic drug treatment and poor glucose control were randomly divided into the observation group and the control group. 50 patients in the observation group were treated with continuous subcutaneous insulin infusion therapy, the other 50 patients in the control group were treated with subcutaneous insulin injections therapy before meals. The efficacy and adverse reactions of two groups were compared and analyzed. Results In the observation group, the blood glucose time, insulin dosage and insulin dosage at blood sugar stable stage of were statistically lower than those in the control group (P0.05). The hypoglycemia reactive and dawn phenomenon of observation were lower than those of the control group, but with no significant difference between the two groups (P0.05). After treatment, the fasting blood glucose, postprandial 2 hour blood glucose and hemoglobin levels of the two groups significantly decreased (P0.05), but the observation group decreased even more significantly (P0.01), and those indicators were also significantly different between the two groups (P0.05). Conclusions Continuous subcutaneous insulin infusion is safe and effective in the treatment of type 2 diabetes, with low incidence of the deputy reaction such as hypoglycemia and dawn phenomenon.
Key concepts: Medicine, Hypoglycemia, Postprandial, Insulin, Hemoglobin, Blood sugar, Subcutaneous injection, Diabetes mellitus