2010•Yufang yixue luntanRequires access

Analysis on Immune Effect of Rabies Vaccination in Wucheng County,2007-2008

Zhao Jin

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Abstract

[Objective] To understand the antibody level in the population by rabies vaccine human immunoglobulin and rabies vaccination in Wucheng county.[Methods]The method for the rabies virus IgG antibody diagnostic kit(ie,enzyme-linked immunosorbent assay)was used.[Results]A total of 448 serum samples were tested,of which 355 were positive,with a total positive rate of 79.24 %.97 were vaccinated within 24 h injured,84 were antibody positive,the positive rate of 86.60%;71 over 24 h inoculated,the antibody positive rate was 80.28%,the difference was not statistically significant(P0.05).The first dose of double to 102 people,the antibody positive rate of 87.25%;178 were 5-dose fully immunized,the antibody positive rate of 70.22%.There was significant difference between the two(P0.01).324 were injury correctly treated,the antibody positive rate of 75.62%;124 were injury incorrectly treated,the antibody positive rate of 70.16%.No significant difference between the two(P0.05).168 were injected with rabies immune globulin after injury,the antibody positive rate of 89.29%;280 were not injected with rabies immune globulin,the antibody positive rate of 76.43%,with statistical difference between the two(P0.01).[Conclusion]In order to achieve better immune effect,after a suspicious animal bite or scratch,the wound should be treated immediately by the medical department,and timely injection of rabies immune globulin and rabies vaccine should be conducted.

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What this paper is about

[Objective] To understand the antibody level in the population by rabies vaccine human immunoglobulin and rabies vaccination in Wucheng county.[Methods]The method for the rabies virus IgG antibody diagnostic kit(ie,enzyme-linked immunosorbent assay)was used.[Results]A total of 448 serum samples were tested,of which 355 were positive,with a total positive rate of 79.24 %.97 were vaccinated within 24 h injured,84 were antibody positive,the positive rate of 86.60%;71 over 24 h inoculated,the antibody positive rate was 80.28%,the difference was not statistically significant(P0.05).The first dose of double to 102 people,the antibody positive rate of 87.25%;178 were 5-dose fully immunized,the antibody positive rate of 70.22%.There was significant difference between the two(P0.01).324 were injury correctly treated,the antibody positive rate of 75.62%;124 were injury incorrectly treated,the antibody positive rate of 70.16%.No significant difference between the two(P0.05).168 were injected with rabies immune globulin after injury,the antibody positive rate of 89.29%;280 were not injected with rabies immune globulin,the antibody positive rate of 76.43%,with statistical difference between the two(P0.01).[Conclusion]In order to achieve better immune effect,after a suspicious animal bite or scratch,the wound should be treated immediately by the medical department,and timely injection of rabies immune globulin and rabies vaccine should be conducted.

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Available abstract

[Objective] To understand the antibody level in the population by rabies vaccine human immunoglobulin and rabies vaccination in Wucheng county.[Methods]The method for the rabies virus IgG antibody diagnostic kit(ie,enzyme-linked immunosorbent assay)was used.[Results]A total of 448 serum samples were tested,of which 355 were positive,with a total positive rate of 79.24 %.97 were vaccinated within 24 h injured,84 were antibody positive,the positive rate of 86.60%;71 over 24 h inoculated,the antibody positive rate was 80.28%,the difference was not statistically significant(P0.05).The first dose of double to 102 people,the antibody positive rate of 87.25%;178 were 5-dose fully immunized,the antibody positive rate of 70.22%.There was significant difference between the two(P0.01).324 were injury correctly treated,the antibody positive rate of 75.62%;124 were injury incorrectly treated,the antibody positive rate of 70.16%.No significant difference between the two(P0.05).168 were injected with rabies immune globulin after injury,the antibody positive rate of 89.29%;280 were not injected with rabies immune globulin,the antibody positive rate of 76.43%,with statistical difference between the two(P0.01).[Conclusion]In order to achieve better immune effect,after a suspicious animal bite or scratch,the wound should be treated immediately by the medical department,and timely injection of rabies immune globulin and rabies vaccine should be conducted.

Key concepts: Rabies, Antibody, Medicine, Vaccination, Immune system, Rabies virus, Population, Immunology

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