Clinical research of improved sequential therapy of eradicating helicobacter pylori

Objective To observe the clinical efficacy and safety of improved sequential therapy on the peptic ulcer patients of helicobacter pylori.Methods 88 patients of the peptic ulcer patients of helicobacter pylori were randomly divided into the treatment group which used the improved sequential therapy and the control group which used standard triple therapy separately.After treatment,patients in each group were observed the ulcer healing rate,the Hp eradicated rate and the adverse reactions.Results The ulcer healing rates of the treatment group and the control group were 95.45% and 88.64% respectively,which were significant difference between the both groups(P0.05).The Hp eradication rate was 90.91% in the treatment group,which raised significantly to the 75.00% of the rate in the control group(P0.05).Conclusion The improved sequential therapy on the peptic ulcer patients of helicobacter pylori has the characteristic of higher eradication rate on Hp,higher ulcer healing rate,more safe,.It has broad application prospects,which can be the first-line therapy on Helicobacter Pylori.