2001•Chinese Journal of Current Advances in General SurgeryRequires access

The expression of MVD in colorectal carcinoma and its clinical significance

Jian Geng

Abstract

To evaluate the expression of microvessel density(MVD) in colorectal carcinoma and its clinical significance.Methods:The Ⅷ Rag expression was measured by S P immunohistochemical method.MVD in the colorectal carcinoma tissue was assayed.Results:Of the 59 cases of colorectal carcinoma studied, MVD was higher expressed in carcinoma with lymph node involvement than that without lymph node involvement(P0 05).The analysis demonstrated that the 5 year survival rate in patients with lower MVD expression was better than that of those with higher MVD expression.Conclusion:The expression of microvessel density has a significant correlation to the biological behavior and prognosis of patients with colorectal carcinoma (P0 05). keywirds

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Key concepts: Medicine, Immunohistochemistry, Colorectal cancer, Clinical significance, Carcinoma, Lymph node, Oncology, Pathology