Investigation of bacteria on burn wounds and their resistance to antibiotics

Objective To investigate bacteria on burn wounds and the results of drug resistance tests.Methods Retrospective investigation was done to 69 burn patients who were treated from the January of 2004 to the April of 2007 in the Department of Burn and Plastic Surgery,First People' s Hospital,Yibin Cit- y,Sichuan.170 strains of bacteria were isolated from the wounds and the dick diffusion method was used to determine drug resistance.Results Totally,122 strains of gram-negative bacteria (71.76%) and 48 stains of gram-positive bacteria (28.24%) were isolated.Among them,the five bacteria identified most often were banmanii (17.00%),Enterobacter cloacae (11.18%),Pseudomonas aeruginosa (10.00%),Staphylococcus aureus (10.59%),and Klebsiella pneumoniae (8.82%).Baumanii made up 23.77% of all the gram-neg- ative bacteria and were tolerant to most antibiotics.Its resistance rate to imipenem was as high as 75.86%. Enterobacter cloacae made up 15.57% of all the gram-negative bacteria and had a high rate (90%) of drug resistance to most antibiotics excluding imipenem.To most antibiotics,Pseudomonas aeruginosa and Kleb- siella pneumoniae had a resistance rate of over 50%.Staphylococcus aureus made up 37.5% of the gram- positive bacteria and had a rate of 17.65% for vaneomycin tolerance.Conclusions Gram-positive bacteria are responsible for most burn wound infections.Bacteria related to burn wound infections are resistant to commonly used antibiotics.Imipenem has comparatively high antibacterial activity to most gram-negative bac- teria,and vancomycin is effective to gram-positive bacteria.