Clinical value of octreotide in treatment of acute bowel obstruction

Objective:To study the effect of otreotide in patients with acute bowel obstruction.Methods:66 cases of acute bowel obstruction were selected and devided into two groups.: treatment group(n=32) and control group(n=34).The patients in control group were treated with fasting,gastrointestinal decompression,clyster,fluid infusion,antibiotics and total parenteral nutrition.The patient in treatment group received hypodermic injection of octreotide(0.1mg,q8h) plus routine therapy,until obstruction was released.The remission time of symptoms,gastrointestinal secretions,the the anal exhaust time and the efficient rate were observed.Results: The remission time of symptoms was(12.1±3.4)hours in treatment group and(34.3±4.1)hours in the control group(P0.01),.while the gastrointestinal drainage after 24 hours was(357±73)ml and(890±95)ml respectively.Moreover,the anal exhaust time in octreotide group(32.5±7.0 h)was shorter than that(58.5±6.2 h)in the routine group notably(P0.01).However,the efficient rate of the two groups was similar(P0.05),with 84.4 percent and 67.6 percent respectively.Conclusion:The use of octreotide,based on routine treatment,can effiectively relieve the symptoms of patients suffering from acute bowel obstruction and promote the recovery of bowel functions.