The clinical analysis of bowel obstruction treated by octreotide

Objective:To investigate the effect of octreotide in patients with bowel obstruction. Methods:93 cases of bowel obstruction selected in our department from February 2007 to January 2009 were divided into two groups: treatment group (45 cases) and control group (48 cases). There was no significant difference on the two groups between age, gender and cause of disease. The patients in the control group were treated with routine therapy including fasting, gastrointestinal decompression, injection of paraffin liquid from gastric tube, intravenous replacement of fluid and electrolytes ,total parenteral nutri tion and antibiotics. The patients in the treatment group received continuous intravenouslyinjection octreotide (25 μg/h) plus routine therapy, until obstruction was released.Investigated the remission of symptoms, the anal exhaust time and the average hospitalization time in the two groups. Results:After treatment, the remission rate of symptoms in the first two days of treatment group was 86.61%, the average annual exhaust time was significantly earlier than that in control group ( P0.05). And the average hospitalization time of treatment group was 3.13 days shorter than that of control group (P0.05). Conclusion: Octreotide is efficient safe in the treatment of bowel obstruction.