2004•Medical Journal of National Defending Forces in Northwest ChinaRequires access
Therapeutic efficacy of valsartan accompanied with metoprolol in the patients with congestive heart failure
Jinlin Su
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Abstract
Objective:To evaluate the therapeutic efficacy of valsartan accompanied with metoprolol in the patients with congestive heart failure(CHF).Methods: 96 patients with CHF were randomly divided into group A ( n =46) who had taken conventional treatment of digitalis and diuretics and group B ( n =50) who were given valsartan (40 to 160 mg·d -1 ) and metoprolol (12.5 to 100 mg·d -1 ) on the conventional therapy.The therapeutic period was 6 months. Results: After treatment,cardiac function (NYHA) improved; blood pressure,heart rate,cardiothoracic ratio,left ventricular diastolic ending diameter (LVDd) and left aurial diameter (LAd) all decreased; left ventricular ejectional fraction (LVEF) increased significantly( P 0.05 ) in group B comparing with those in group A. There were few side effects and patients' tolerance was perfect in Group B.Conclusion:The therapeutic efficacy of valsartan accompanied with metoprolol in the patients with congestive heart failure(CHF) is satisfactory. There are few side effects.