The experiment reserch of angiogenes effect of Tongxinluo capsule on the chick embryo chorioallantoic membrane model

Objective To study the stimulate angiogenes effect of Tongxinluo capsule on the chick embryo chorioallantoic membrane (CAM) model.Methods 32 chick embryo (CE) were randomly divided into 4 groups,8 CE in group A were treated with vacuity blood serum as negative controls,8 CE in group B were treated with basic Fibroblast Growth Facter as positive controls,8 CE in group C and 8 CE in group D were treated with maxiums and micro dose of Tongxinluo herbal serum respectively.After 3 days of incubated,count the first and second grade vessels.Results The proliferation of vessels in group C was obviously increase than that in group A (P0.05) and almost equaled to that of group B (P0.05),but group D has no obviously difference compared with group A (P 0.05 ).Conclusion Tongxinluo capsule can stimulate angiogenesis of the Chick embryo CAM model.