2003Chinese New Drugs JournalRequires access

The clinical efficacy of hydrocortisone buteprate cream in treatment of dermatitis and eczema

Zhong Xiang

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Abstract

Objective:To observe the efficacy and safety of hydrocortisone buteprate cream (Pan-del) intreatment of dermatits and eczema. Methods: The randomized, controlled, open trial was conducted in 308 patients with dermatitis or eczema. They were divided to receive enternal application of Pandel tid for 3-25d (n = 188) or hydrocortisone butyrate cream tid for 3-25d. Results: The effective rate, cure rate, and incidence of adverse reaction for Pandel group were 93.6% ,77.7% , and 7.4% respectively,and for hydrocortisone butyrate cream group were 92.5% ,75.0% and 8.4% respectively . No significant difference was observed between groups in efficacy and safety (P 0. 05). Conclusion :Hydrocortisone buteprate cream is effective in treatment of dermatitis and eczema.

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What this paper is about

Objective:To observe the efficacy and safety of hydrocortisone buteprate cream (Pan-del) intreatment of dermatits and eczema. Methods: The randomized, controlled, open trial was conducted in 308 patients with dermatitis or eczema. They were divided to receive enternal application of Pandel tid for 3-25d (n = 188) or hydrocortisone butyrate cream tid for 3-25d. Results: The effective rate, cure rate, and incidence of adverse reaction for Pandel group were 93.6% ,77.7% , and 7.4% respectively,and for hydrocortisone butyrate cream group were 92.5% ,75.0% and 8.4% respectively . No significant difference was observed between groups in efficacy and safety (P 0. 05). Conclusion :Hydrocortisone buteprate cream is effective in treatment of dermatitis and eczema.

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Available abstract

Objective:To observe the efficacy and safety of hydrocortisone buteprate cream (Pan-del) intreatment of dermatits and eczema. Methods: The randomized, controlled, open trial was conducted in 308 patients with dermatitis or eczema. They were divided to receive enternal application of Pandel tid for 3-25d (n = 188) or hydrocortisone butyrate cream tid for 3-25d. Results: The effective rate, cure rate, and incidence of adverse reaction for Pandel group were 93.6% ,77.7% , and 7.4% respectively,and for hydrocortisone butyrate cream group were 92.5% ,75.0% and 8.4% respectively . No significant difference was observed between groups in efficacy and safety (P 0. 05). Conclusion :Hydrocortisone buteprate cream is effective in treatment of dermatitis and eczema.

Key concepts: Medicine, Hydrocortisone, Dermatology, Clinical efficacy, Cure rate, Randomized controlled trial, Incidence (geometry), Skin reaction

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