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2010•Huaxi yixueRequires access

Clinical Significance of Serum Ferritin and β2-MG Detection in Children with Acute Lymphoblastic Leukemia

Peng Min-zh

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Abstract

Objective To observe the dynamic changes of Serum Ferritin( SF) and β2-MG levels in children with acute lymphoblastic leukemia( ALL) and to investigate its clinical significance on clinical curative effect. Methods Fifty-three in-patients with ALL,28 relieved patients from July 2008 to April 2010 in our Hematology and 30 normal as control were selected in our study. The venousblood of patients and controls were extract in order to detect SF and β2-MG. Results Before the treatment,the level of SF and β2-MG in ALL group were significantly higher than those in the control group ( P 0. 01). After the treatment,the level of SF and β2-MG in ALL group decreased significantly ( P 0. 01) ,and they return to normal level gradually with the outcome; compared with before the treatment,the differences were statistically significant( P 0. 01). Conclusion SF and β2-MG can be used as a helpful indicator to evaluate the therapeutic effect of ALL.

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What this paper is about

Objective To observe the dynamic changes of Serum Ferritin( SF) and β2-MG levels in children with acute lymphoblastic leukemia( ALL) and to investigate its clinical significance on clinical curative effect. Methods Fifty-three in-patients with ALL,28 relieved patients from July 2008 to April 2010 in our Hematology and 30 normal as control were selected in our study. The venousblood of patients and controls were extract in order to detect SF and β2-MG. Results Before the treatment,the level of SF and β2-MG in ALL group were significantly higher than those in the control group ( P 0. 01). After the treatment,the level of SF and β2-MG in ALL group decreased significantly ( P 0. 01) ,and they return to normal level gradually with the outcome; compared with before the treatment,the differences were statistically significant( P 0. 01). Conclusion SF and β2-MG can be used as a helpful indicator to evaluate the therapeutic effect of ALL.

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Available abstract

Objective To observe the dynamic changes of Serum Ferritin( SF) and β2-MG levels in children with acute lymphoblastic leukemia( ALL) and to investigate its clinical significance on clinical curative effect. Methods Fifty-three in-patients with ALL,28 relieved patients from July 2008 to April 2010 in our Hematology and 30 normal as control were selected in our study. The venousblood of patients and controls were extract in order to detect SF and β2-MG. Results Before the treatment,the level of SF and β2-MG in ALL group were significantly higher than those in the control group ( P 0. 01). After the treatment,the level of SF and β2-MG in ALL group decreased significantly ( P 0. 01) ,and they return to normal level gradually with the outcome; compared with before the treatment,the differences were statistically significant( P 0. 01). Conclusion SF and β2-MG can be used as a helpful indicator to evaluate the therapeutic effect of ALL.

Key concepts: Medicine, Lymphoblastic Leukemia, Internal medicine, Clinical significance, Gastroenterology, Serum ferritin, Ferritin, Hematology

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