Expression and clinical significance of serum Ferritin and β_2-microglobulin in patients with infectious diseases

Objective To investigate the levels of serum Ferritin(SF) and β2- microglobulin(β2-MG) in patients with infectious diseases.Methods From January 2012 to January 2013 in Beijing Electric Power Hospital of North China Grid Limited Company,60 patients with infectious diseases were as infection group,which the mainly infection was bacterial infection with etiological basis,and 60 patients from clinic physical examination were as control group.Then,the levels of SF and β2-MG in two groups were measured and compared.Results SF levels of infection group was(325.85±189.10) μg/L,and β2-MG levels was(3.92±2.20) mg/L,both of them were significantly higher than those of control group [SF(130.95±77.40) μg/L,β2-MG(2.02±0.59) mg/L],the differences were statistically significant(P 0.01).After treatment,54 cases improved,6 patients died,but the levels of SF,β2-MG of two groups were compared,the differences were not statistically significant(P 0.05).Conclusion SF and β2-MG concentration determination is guiding significance to the early infectious decision and the rational using antibiotic.