2010•The Journal of Pharmaceutical PracticeRequires access

Studies on the chemical constituents of Ainsliaea macrocephala

Yunheng Shen

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Abstract

Objective To study the chemical constituents of Ainsliaea macrocephala(Franch).Methods The isolation and purification were carried out by extraction,silica gel and Sephadex LH-20 column chromatography.The compounds were identified on the basis of spectral analysis,including IR,1H-NMR,13C-NMR and MS.Results Six compounds were obtained from petrol ether fraction of ethnol extract of Ainsliaea macrocephala and their structures were determined as simiarenol(1),stigmasterol(2),Bis(2-ethylhexy1) phthalate(3),octadecanoic acid(4),2-hydroxy-linolenic acid(5),glycerol-tri-9-octadecenoate(6).Conclusion Compounds(1)~(6) were isolated from this plant for the first time.

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What this paper is about

Objective To study the chemical constituents of Ainsliaea macrocephala(Franch).Methods The isolation and purification were carried out by extraction,silica gel and Sephadex LH-20 column chromatography.The compounds were identified on the basis of spectral analysis,including IR,1H-NMR,13C-NMR and MS.Results Six compounds were obtained from petrol ether fraction of ethnol extract of Ainsliaea macrocephala and their structures were determined as simiarenol(1),stigmasterol(2),Bis(2-ethylhexy1) phthalate(3),octadecanoic acid(4),2-hydroxy-linolenic acid(5),glycerol-tri-9-octadecenoate(6).Conclusion Compounds(1)~(6) were isolated from this plant for the first time.

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Available abstract

Objective To study the chemical constituents of Ainsliaea macrocephala(Franch).Methods The isolation and purification were carried out by extraction,silica gel and Sephadex LH-20 column chromatography.The compounds were identified on the basis of spectral analysis,including IR,1H-NMR,13C-NMR and MS.Results Six compounds were obtained from petrol ether fraction of ethnol extract of Ainsliaea macrocephala and their structures were determined as simiarenol(1),stigmasterol(2),Bis(2-ethylhexy1) phthalate(3),octadecanoic acid(4),2-hydroxy-linolenic acid(5),glycerol-tri-9-octadecenoate(6).Conclusion Compounds(1)~(6) were isolated from this plant for the first time.

Key concepts: Chemistry, Sephadex, Column chromatography, Stigmasterol, Chemical constituents, Chromatography, Silica gel, Ether

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