ScholarLens Back to search
2006•Zhongguo linchuang yaolixue yu zhiliaoxueRequires access

Protective effects of Chishaogancaochongji on chemical liver injury induced by D-galactosamine in mice

Cen De-yi

Open publisher page 1 citations

Abstract

AIM: To investigate the effects of Chishaoganaochongji D-galactosamine-induced liver injury in mice.METHODS: The chemical-associated liver injury in mouse was induced made by administration of D-GalN.The serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) level,and malondiadehyde(MDA) and nitric oxide(NO) level in liver homogenate were assayed by chemochromometry.RESULTS:Chishaogancaochongji(200,400,800(mg·kg~(-1))) was able to decrease levels of serum transaminases(ALT,AST),liver index and thymus index significantly.Furthermore,Chishaogancaochongji also decreased MDA content and NO level in liver homogenate.CONCLUSION: Chishaogancaochongji has protective effect on chemical-associated liver injury in mice.

About this research paper

What this paper is about

AIM: To investigate the effects of Chishaoganaochongji D-galactosamine-induced liver injury in mice.METHODS: The chemical-associated liver injury in mouse was induced made by administration of D-GalN.The serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) level,and malondiadehyde(MDA) and nitric oxide(NO) level in liver homogenate were assayed by chemochromometry.RESULTS:Chishaogancaochongji(200,400,800(mg·kg~(-1))) was able to decrease levels of serum transaminases(ALT,AST),liver index and thymus index significantly.Furthermore,Chishaogancaochongji also decreased MDA content and NO level in liver homogenate.CONCLUSION: Chishaogancaochongji has protective effect on chemical-associated liver injury in mice.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

AIM: To investigate the effects of Chishaoganaochongji D-galactosamine-induced liver injury in mice.METHODS: The chemical-associated liver injury in mouse was induced made by administration of D-GalN.The serum alanine aminotransferase(ALT) and aspartate aminotransferase(AST) level,and malondiadehyde(MDA) and nitric oxide(NO) level in liver homogenate were assayed by chemochromometry.RESULTS:Chishaogancaochongji(200,400,800(mg·kg~(-1))) was able to decrease levels of serum transaminases(ALT,AST),liver index and thymus index significantly.Furthermore,Chishaogancaochongji also decreased MDA content and NO level in liver homogenate.CONCLUSION: Chishaogancaochongji has protective effect on chemical-associated liver injury in mice.

Key concepts: Liver injury, Galactosamine, Nitric oxide, Alanine aminotransferase, Chemistry, Pharmacology, Alanine transaminase, Internal medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Protective effects of Chishaogancaochongji on chemical liver injury induced by D-galactosamine in mice — Research Paper | ScholarLens