2011•Proceeding of Clinical MedicineRequires access

Study on the strain of pseudomonas aeruginosa with multi-drug resistance gene

Yongan Zhou

Abstract

Objective:To study the instance and mechanism of multi-drug resistance of pseudomonas aeruginosa.Methods:The genes of multi-drug resistance including beta-lactamase,aminoglycosides modifying enzymes,chloramphenicol,disinfect resistance and sulfanilamide-resistance were determined by polymerase chain reaction(PCR).Results:The results of PCR indicated that TEM,MIR,CTX-M1,OXA-1,OXA-10,aac(6′)-Ⅰb,aac(6′)-Ⅰ,aac(3)-Ⅱ,ant(2″)-Ⅰ,catB,qacE △1-sul1 genes were positive,while GES,DHA-2,VEB,cmlA genes were negative,Opr D2 is not missing.Conclusion:There are multi-drug resistance genes in the strain of pseudomonas aeruginosa,which resist disinfectant of amines and guanidines.

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Key concepts: Pseudomonas aeruginosa, Microbiology, Gene, Drug resistance, Sulfanilamide, Strain (injury), Drug, Biology