Relationship Between sPLA2,hs-CRP and CK-MB in Coronary Heart Disease and Its Clinical Value

[Objective] To observe the changes of serum secretary type II phospholipase(sPLA2),high sensitive C-reactive protein(hs-CRP)and MB isoenzyme of creatine kinase(CK-MB)in patients with coronary heart disease and to analyze their correlation.[Methods] Serum levels of sPLA2,hs-CRP and CK-MB were detected in 28 patients with stable angina(SA),54 patients with unstable angina(UA),22 patients with acute myocardial infarction(AMI)and 20 patients with normal coronary artery(NS).[Results] Serum levels of sPLA2 and hs-CRP increased significantly in AMI group compared with those in SA and UA groups.CK-MB increased significantly in AMI group,and it was higher than that in both SA and UA groups,which there was no statistical significant difference between them.[Conclusion] sPLA2,hs-CRP and CK-MB present positive correlation.The obviously increasing of sPLA2,hs-CRP and CK-MB is useful for the diagnosis of AMI,and the increasing of sPLA2 and hs-CRP is useful to distinguish SA and UA.