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2011•China Medical HeraldRequires access

Expression and clinical significance of CD44v6 and MMP-9 in adenoid cystic carcinoma

Hongliang Qi

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Abstract

Objective: To study the expression and clinical significance of matrix metalloproteinase-9(MMP-9) and endoglin(CD44v6)in adenoid cystic carcinoma(ACC).Methods: Immunohistochemistry was used to measure the expression of CD44v6 and MMP-9 in ACC,calculation of CD44v6 and MMP-9,the data was analyzed by SPSS 17.0 software package.Results: The grading difference of CD44v6 and MMP-9 in normal salivary gland and adenoid cystic carcinoma was significant;As was also found in different pathological type of adenoid cystic carcinoma.Conclusion: CD44v6 expression is correlated with the pathological type of ACC,MMP-9 is highly expressed in ACC tissues,it might become promising targets for adenoid cystic carcinoma.

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What this paper is about

Objective: To study the expression and clinical significance of matrix metalloproteinase-9(MMP-9) and endoglin(CD44v6)in adenoid cystic carcinoma(ACC).Methods: Immunohistochemistry was used to measure the expression of CD44v6 and MMP-9 in ACC,calculation of CD44v6 and MMP-9,the data was analyzed by SPSS 17.0 software package.Results: The grading difference of CD44v6 and MMP-9 in normal salivary gland and adenoid cystic carcinoma was significant;As was also found in different pathological type of adenoid cystic carcinoma.Conclusion: CD44v6 expression is correlated with the pathological type of ACC,MMP-9 is highly expressed in ACC tissues,it might become promising targets for adenoid cystic carcinoma.

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Available abstract

Objective: To study the expression and clinical significance of matrix metalloproteinase-9(MMP-9) and endoglin(CD44v6)in adenoid cystic carcinoma(ACC).Methods: Immunohistochemistry was used to measure the expression of CD44v6 and MMP-9 in ACC,calculation of CD44v6 and MMP-9,the data was analyzed by SPSS 17.0 software package.Results: The grading difference of CD44v6 and MMP-9 in normal salivary gland and adenoid cystic carcinoma was significant;As was also found in different pathological type of adenoid cystic carcinoma.Conclusion: CD44v6 expression is correlated with the pathological type of ACC,MMP-9 is highly expressed in ACC tissues,it might become promising targets for adenoid cystic carcinoma.

Key concepts: Adenoid cystic carcinoma, Medicine, Grading (engineering), Pathological, Pathology, Immunohistochemistry, Carcinoma, Matrix metalloproteinase

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Expression and clinical significance of CD44v6 and MMP-9 in adenoid cystic carcinoma — Research Paper | ScholarLens