Optimization of extraction technology of Xianci capsules by orthogonal test

Objective To optimize the extraction process of Xianci capsules.Methods Extraction yields of solid drug and scutellarin were regarded as the investigation index,and duration on extraction,extraction times and the amount of water were evaluated by orthogonal experimental design,and the best extraction process was statistically analyzed and screened by multi-index comprehensive evaluation method.Results Number of extractions had notable effect on experimental results,while the amount of water and the duration of extraction had no notable effects.Considering the effects of the 3 factors and actual production process synthetically,the optimum condition of extraction process was 2 times of water,10 times of water,extraction time 0.5 h and extracting 3 times.Conclusion The optimum extraction process is reasonable,which provide the scientific basis for the preparation of Xianci capsules.