Optimization of extraction process on Xiancidan prescription by orthogonal design

Objective To optimize the extract process for Xiancidan prescription.Methods Dry extract yield and the retention rates of scutellarin were used as indexes,HPLC was used to quantify,and the effects of extraction time,the amount of water,extracting times,and degree on extraction technology were evaluated by L9(34) orthogonal test.Results The optimum technical parameters of the water extracting technology were as follows: circumfluence extracting for 3 times with 12,10,and 10 times the amount of water,0.5 h per time.Conclusion The preparation procedure is stable and feasible and it can be used for the extraction of Xiancidan prescription.