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Optimization of Extraction Process of Yunkuntong Capsules by Orthogonal Design

Wen Zhi-yun

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Abstract

Objective To investigate the optimal extraction process of Yunkuntong capsules.Methods The orthogonal design was used in the ultrasonic extraction,with the volume of water,extraction times and extraction time as factors.The content of paeoniflorin was detected by HPLC method to determine the best extraction technology.Results The optimal process was performed by 2 h extraction for 2 times,with 10-fold volume of water.Conclusion The preperetion process is stable,feasible and reasonable.

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Objective To investigate the optimal extraction process of Yunkuntong capsules.Methods The orthogonal design was used in the ultrasonic extraction,with the volume of water,extraction times and extraction time as factors.The content of paeoniflorin was detected by HPLC method to determine the best extraction technology.Results The optimal process was performed by 2 h extraction for 2 times,with 10-fold volume of water.Conclusion The preperetion process is stable,feasible and reasonable.

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Available abstract

Objective To investigate the optimal extraction process of Yunkuntong capsules.Methods The orthogonal design was used in the ultrasonic extraction,with the volume of water,extraction times and extraction time as factors.The content of paeoniflorin was detected by HPLC method to determine the best extraction technology.Results The optimal process was performed by 2 h extraction for 2 times,with 10-fold volume of water.Conclusion The preperetion process is stable,feasible and reasonable.

Key concepts: Paeoniflorin, Extraction (chemistry), Chromatography, Process (computing), Volume (thermodynamics), Water extraction, High-performance liquid chromatography, Process engineering

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