The effect of propofol combining with fentanyl on artificial abortion

Objective To compare the effect of propofol and combining propofol with fentanyl for artificial abortion. Methods Four hundreds patients scheduled for painless artificial abortion were randomized to two groups:1.5 mg/kg of propofol (Group P) or 0.05 mg of fentany and 1.5 mg/kg of propofol (Group F) were administered respectively. Bolus propofol 20-30 mg was added when the patient moved during the operation. Intraoperative heart rate and blood pressure were monitored. Ephedrine added as needed.Operation time,total consumption of propofol,time of wakening, time of stay in the operation room and postoperative uterine contraction pain were recorded. Results Total comsumption of propofol was less in Group F than that in Group P(P0.01).Whereas postoperative uterine contraction pain in Group F was lower than that in Group P(P0.01).There were no differences between the two groups in SpO2, time of waking,time of stay in the operation room and the rate of nausia and vomiting.Conclusion Combining fentanyl and propofol can reduce the consumption of anesthetics comparing to propofol alone for patient of painless arfificial abortion.