Analysis of drug resistance and distribution in Escherichia coli from urine

Objective: To investigate drug resistance and clinical distribution of E.coli isolated from urine in hospital,and to provide the guidance for the rational clinical application of antibiotics.Methods:161 strains of E.coli were isolated from urine from June 2010-February 2011,whose drug resistance rates and clinical distribution were analyzed retrospectively.Results: 161 strains of E.coli were collected mainly from the Department of Urology(62.7%),Intensive Care Unit(13%) and Medical Wards(10%).Resistance rates to imipenem,meropenem,ertapenem,piperacillin/tazobactam,cefoxitin,cefepime,ceftazidime,aztreonam,amoxicillin/clavulanic,cefotaxime,tobramycin,cidomycin,levofloxacin,ciprofloxacin,SMZ-TMP,cefazolin,furadantin and ampicillin were 0.00%,0.00%,0.00%,5.6%,16.8%,23%,26.7%,33.5%,43.5%,48.4%,50.9%,52.8%,60.9%,62.1%,73.9%,80.7%,90.1% and 92.5%.Conclusion: E.coli is common pathogen which can cause urinary tract infection and the antibiotics should be chosen according to drug sensitivity test in the clinical practice.