Analysis of drug resistance and distribution in 842 strains of Escherichia coli

Objective: To investigate drug resistance and specimen source of Escherichia coli in hospital,thus guiding clinical treatment and controlling nosocomial infection.Methods: 842 strains of Escherichia coli were collected from Taian Central Hospital from January to November in 2011,whose drug resistance rates and specimen source were analyzed retrospectively.Results: Resistance rates of the 842 strains of Escherichia coli to Imipenem,meropenem,Ertapenem,piperacillin/tazobactam,amikacin,Cefoxitin,Amoxicillin/ Clavulanic,cefepime,ceftazidime,aztreonam,cidomycin,tobramycin,levofloxacin,ciprofloxacin,Cefotaxime,SMZ-TMP,Cefazolin and Ampicillin were 0.24%,0.24%,0.24%,9.6%,17%,23%,33%,40%,43.3%,48%,54.2%,54.3%,56%,59%,60%,65%,76% and 84.7% respectively.842 strains of Escherichia coli were mainly detected from urine(31.8%) and sputum(28.6%).Conclusion: Escherichia coli are common pathogen which can cause infection in respiratory tract and urinary tract.Antibiotics should be chosen according to drug sensitivity test in the clinical practice.