Analysis of the relationship between severity degree of coronary lesions and hyperuricemia in elderly patients

Objective To study the relationship between the severity degree of coronary lesions and serum level of uric acid in elderly patients. Methods Coronary angiography measurement was performed in 164 elderly subjects,who were classified into coronary heart disease(CHD) group and normal control group.The serum level of uric acid was measured by uric acid enzyme method.The relationship between the severity degree of coronary lesions and serum level of uric acid was analyzed by using linear correlation and multiple stepwise regression. Results The serum level of uric acid of CHD group was significantly higher than that of normal control group(P0.01).The linear correlation analysis showed serum level of uric acid was significantly correlated with the severity degree of coronary lesions.The multiple stepwise regression analysis showed serum level of uric acid was an independently related factor of coronary lesions. Conclusions Increased serum level of uric acid is a risk factor to CHD in the elderly.